Parasitology

Dr. William K. Anyan

Dr. William K. Anyan

Parasitology Department

Name: WILLIAM KOFI ANYAN (PhD)

Research Area Strengths (List): Schistosomiasis, Neglected Tropical Diseases, Vector-borne diseases, Malaria

Email(s): wanyan@noguchi.ug.edu.gh

Research Group(s):

Neglected Tropical Diseases (NTD), One Health, Vector Research

 

Ongoing Research(s)

Project title: Drug discovery based on medicinal plants for selected NTDs and drug-resistant pathogens in Ghana

Amount:  75,000,000 Jpn Yen

Agency: Japan Agency for Medical Research and Development

Date: March 2016- March 2021

Role: Co-PI

Affiliated Departments/Institutions:

Department of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana.

Professional Organizations:

2009 – Current: American Society for Tropical Medicine and Hygiene 

Research Interests (250 words maximum): My primarily interest is in parasite immunology focusing on Neglected Tropical Diseases (NTDs) particularly schistosomiasis, trypanosomiasis and Soil Transmitted Helminths (STH), as well as malacology. Currently I am involved with drug discovery related studies for schistosomiasis and diagnostics-development of monoclonal antibodies and evaluation of RDTs for malaria.

My other research interests include host-parasite relationship, and understand the role played by various cells in contributing to pathology and/or protection.

Current Research Supervision:

MPhil

2017-2018            Ninette Owusu-Adzorah (Mrs.)

College of Allied Health Sciences, University of Cape Coast

Thesis title: Evaluating the efficacy of five medicinal plants extracts for the control of and prevention of schistosomiasis

 

Notable Publications

  1. Mitsuko Ohashi, Michael Amoa-Bosompem, Kofi Dadzie Kwofie, Jefferey Agyapong,

Richard Adegle, Maxwell Mamfe Sakyiamah, Frederick Ayertey, Kofi Baffuor‐Awuah Owusu, Isaac Tuffour, Philip Atchoglo, Nguyen Huu Tung, Takuhiro Uto, Frederick Aboagye, Alfred Ampomah Appiah, Regina Appiah-Opong, Alexander K. Nyarko, |William Kofi Anyan, Irene Ayi, Daniel Adjei Boakye, Kwadwo Ansah Koram, Dominic Edoh, Shoji Yamaoka, Yukihiro Shoyama, Nobuo Ohta (2018) In vitro antiprotozoan activity and mechanism of action of selected Ghanaian medicinal plants against Trypanosoma, Leishmania and Plasmodium parasites. Phytotherapy Research. 32:1617–1630

2. Lodh N, Mikita K, Bosompem KM, Anyan WK, Quartey JK, Otchere J, Shiff CJ (2017)  Point of care diagnosis of multiple schistosome parasites: Species-specific DNA detection in urine by loop-mediated isothermal amplification (LAMP). Acta Trop. 173:125-129

  1. Linda A. O. Amoah, William K. Anyan, Fredrick Aboagye-Antwi, Severin Abonie, Mabel D. Tettey and Kwabena M. Bosompem (2017). Environmental Factors and their Influence on Seasonal variations of Schistosomiasis Intermediate Snail Hosts Abundance in Weija Lake, Ghana. AJournal of Advocacy Research and Education. 4(2):68-80.
  2. Emmanuel Mouafo Tekwu, Kwabena Mante Bosompem, William Kofi Anyan, Regina Appiah-Opong, Kofi Baffour-Awuah Owusu, Mabel Deladem Tettey, Felicia Amanfo Kissi, Alfred Ampomah Appiah, Veronique Penlap Beng, and Alexander Kwadwo Nyarko (2017). In Vitro Assessment of Anthelmintic Activities of Rauwolfia vomitoria (Apocynaceae) Stem Bark and Roots against Parasitic Stages of Schistosoma mansoni and Cytotoxic Study. Journal of Parasitology Research 60(6)
  3. Emmanuel Mouafo Tekwu, William Kofi Anyan, Daniel Boamah, Kofi Owusu Baffour-Awuah, Stephanie Keyetat Tekwu, Veronique Penlap Beng, Alexander Kwadwo Nyarko and Kwabena Mante Bosompem (2016). Mechanically produced schistosomula as a higher-throughput tools for phenotypic pre-screening in drug sensitivity assays: current research and future trends. Biomarker Research 4:21
  4. Kofi D. Kwofie, Nguyen Huu Tung, Mitsuko Suzuki-Ohashi, Michael Amoa-Bosompem, Richard Adegle, Maxwell M. Sakyiamah, Frederick Ayertey, Kofi Baffour-Awuah Owusu, Isaac Tuffour, Philip Atchoglo, Kwadwo K. Frempong, William K. Anyan, Takuhiro Uto, Osamu Morinaga, Taizo Yamashita, Frederic Aboagye, Alfred A. Appiah, Regina Appiah-Opong, Alexander K. Nyarko, Yasuchika Yamaguchi, Dominic Edoh, Kwadwo A. Koram, Shoji Yamaoka, Daniel A. Boakye, Nobuo Ohta, Yukihiro Shoyama, Irene Ayi (2016). Antitrypanosomal activities and mechanisms of action of novel tetracyclic iridoids from Morinda lucida benth. America Society for Microbiology 60(6):2383-90
  5. Suzuki Mitsuko, Tung Nguyen Huu, Kwofie Kofi D, Adegle Richard, Amoa-Bosompem Michael, Sakyiamah Maxwell, Ayertey Frederick, Owusu Kofi Baffour-Awuah, Tuffour Isaac, Atchoglo Philip, Frempong Kwadwo Kyereme, Anyan William K, Uto Takuhiro, Morinaga Osamu, Yamashita Taizo, Aboagye Frederic, Appiah, Alfred Ampomah, Appiah-Opong Regina, Nyarko Alexander K, Yamaoka Shoji, Yamaguchi Yasuchika, Edoh Dominic, Koram Kwadwo, Ohta Nobuo, Boakye Daniel A., Ayi Irene, Shoyama Yukihiro (2015). New anti-trypanosomal active tetracyclic iridoid isolated from Morinda lucida Benth. Bioorg Med Chem Lett ;25(15):3030-3
  1. William K. Anyan, Takenori Seki, Takashi Kumagai, Kazushige Obata-Ninomiya,Rieko Furushima-Shimogawara, Bethel Kwansa-Bentum, Nobuaki Akao, Kwabena M. Bosompem,Daniel A. Boakye, Michael D. Wilson, Hajime Karasuyama, Nobuo Ohta (2013). Basophil depletion downregulates Schistosoma mansoni egg-induced granuloma formation. Parasitology International 62(6):508-13.
  2. Takenori Seki, Takashi Kumagai, Bethel Kwansa-Bentum, Rieko Furushima-Shimogawara, William K. Anyan, Yuuki Miyazawa, Yoichiro Iwakura and Nobuo Ohta (2012). IL-4/IL-13 suppress excessive neutrophil infiltration and hepatocyte damage during acute murine schistosomiasis japonica. Infection and Immunity. America Society for Microbiology, 79 (12).
  3. William K. Anyan, Takashi Kumagai, Rieko F. Shimogawara, Takenori Seki, Nobuaki Akao, Kazushige Obata, Bethel Kwansa-Bentum, Kwabena Mante Bosompem, Daniel G Boakye, Michael D. Wilson, Hajime Karasuyama, Nobuo Ohta (2010). Schistosome eggs have a direct role for induction of basophils capable of high level of IL-4 production: Comparative study of single- and bisexual infection of Schistosoma mansoni in vivo. Tropical Medicine and Health. 38(1):13-23

The Noguchi Memorial Institute for Medical Research (NMIMR), set up in 1979 as a semi autonomous institute of the University, is the leading biomedical research facility in Ghana.

© 2017 NMIMR

Other Links

Get In Touch