Research Fellows

Search Our Site

+233 030 2501178/79

Title

Dr.

Name

Adwoa Asante-Poku

Academic Qualification

B.Sc., M.Phil. (Ghana), Ph.D. (Switzerland)

Professional Qualification

Molecular Biologist

Email address

aasante-poku@noguchi.ug.edu.gh

Telephone (Office)

+233-302-501178/9

Cell Phone

0271858627

Fax number

+233-302-502128/513202

School/Institute

Noguchi Memorial Institute for Medical Research

Department:

Bacteriology

Biography

Dr Adwoa Asante-Poku Wiredu joined the department of Bacteriology, NMIMR in 2003 as a research assistant and for the past 10 years has worked on various bacteria diseases including Chlamydia Trachomatis, Diahorroea pathogens, Buruli Ulcer and currently TB. During these years, she got acquainted to various public health issues associated with these diseases. She have been fascinated about how diseases interact with both the environment and with their host as well as the various strategies adopted to control them. In 2009, she undertook further training in molecular biology techniques at the institute for infectious Diseases, Bern, Switzerland where she learnt DNA finger printing techniques for genotyping TB strains which she successfully established at NMIMR. Her current interest in Tuberculosis arose when she got to know about its health burden. Dr Adwoa Asante-Poku Wiredu holds a PhD in Microbiology from the University of Basel, Switzerland. During her PhD studies, she established several DNA fingerprinting assays such as SNP genotyping, large sequence analysis and cost effective MIRU-VNTR assay at the Department of Bacteriology for genotyping TB strains in Ghana. With these tools she provided for the first time, information on different TB genotypes circulating in Ghana that is essential for the effective control of TB.  She also has B.Sc. (2000) and M.Phil. (2005) Degrees from the University of Ghana, Legon.

Administrative Role

N/A

Research interests

  1. Host and Pathogen Interactions.
  2. Molecular Epidemiology of Mycobacterial diseases of Public Health Importance.

Completed research projects

N/A

On-going projects

1.      Genotypic characterization of Mycobacterium tuberculosis in Ghana, project 2012-2017, Funded by Wellcome Trust; Coordinator

2.      Host susceptibility to Tuberculosis (TB) in Ghana. 2016-2019 Principal investigator

Peer-reviewed publications

1.            Otchere ID, Asante-Poku A, Osei-Wusu S, Baddoo A, Sarpong E, Ganiyu AH, Aboagye SY, Forson A, Bonsu F, Yahayah AI, Koram K, Gagneux S, Yeboah-Manu D. Detection and characterization of drug-resistant conferring genes in Mycobacterium tuberculosis complex strains: A prospective study in two distant regions of Ghana..Tuberculosis (Edinb). 2016 Jul; 99:147-54. doi: 10.1016/j.tube.2016.05.014. Epub 2016 Jun 3.

 

2.            Lamelas A, Ampah KA, Aboagye S, Kerber S, Danso E, Asante-Poku A, Asare P, Parkhill J, Harris SR, Pluschke G, Yeboah-Manu D, Röltgen K.Spatiotemporal Co-existence of Two Mycobacterium ulcerans Clonal Complexes in the Offin River Valley of Ghana. PLoS Negl Trop Dis. 2016 Jul 19;10(7):e0004856. doi: 10.1371/journal.pntd.0004856. eCollection 2016 Jul.

 

3.            Asante-Poku A, Otchere ID, Danso E, Mensah DD, Bonsu F, Gagneux S, Yeboah-Manu D. Establishment and evaluation of the genotype MTBDRplus for rapid detection of drug resistant tuberculosis in Ghana. Int J Tuberc Lung Dis. 2015 Aug; 19(8): 954-9.

 

4.            Asante-Poku A, Yeboah-Manu D, Otchere ID, Aboagye SY, Stucki D, Hattendorf J, Borrell S, Feldmann J, Danso E, Gagneux S. Mycobacterium africanum is associated with patient ethnicity in Ghana. PLoS Negl Trop Dis. 2015 Jan 8; 9(1): e3370

 

5.            Asante-Poku A, Aning KG, Boi-Kikimoto B, Yeboah-Manu D. Prevalence of Bovine tuberculosis in a dairy cattle farm and a research farm in Ghana. Onderstepoort J Vet Res. 2014 Apr 23; 81(2): E1-6.

 

6.            Asante-Poku A, Nyaho MS, Borrell S, Comas I, Gagneux S, Yeboah-Manu D. Evaluation of customized lineage-specific sets of MIRU-VNTR loci for genotyping Mycobacterium tuberculosis complex isolates in Ghana. PLoS One. 2014 Mar 25; 9(3): e92675

 

7.            Yeboah-Manu D, Asante-Poku A, Ampah K, Kpeli G, Danso E, Owusu-Darko K, Bonsu FA. Drug susceptibility pattern of Mycobacterium tuberculosis isolates from Ghana; correlation with clinical response. Mycobacterial diseases. 2012 April; 2:107.

 

8.            Yeboah-Manu D, Röltgen K, Opare W, Asan-Ampah K, Quenin-Fosu K, Asante-Poku A, Ampadu E, Fyfe J, Koram K, Ahorlu C, Pluschke G. Sero-epidemiology as a tool to screen populations for exposure to Mycobacterium ulcerans. PLoS Negl Trop Dis. 2012 Jan; 6(1): e1460.

 

9.            Yeboah-Manu D, Asante-Poku A, Asan-Ampah K, Ampadu ED, Pluschke G. Combining PCR with microscopy to reduce costs of laboratory diagnosis of Buruli Ulcer Am J Trop Med Hyg. 2011 Nov; 85(5): 900-4.

 

10.        Yeboah-Manu D, Asante-Poku A, Bodmer T, Stucki D, Koram K, Bonsu F, Pluschke G, Gagneux S. Genotypic diversity and drug susceptibility patterns among M. tuberculosis complex isolates from South-Western Ghana PLoS One. 2011 Jul; 6(7): e21906.

 

11.        Yeboah-Manu D, Danso E, Ampah K, Asante-Poku A, Nakobu Z, Pluschke G. Isolation of Mycobacterium ulcerans from swab and fine-needle-aspiration specimens J Clin Microbiol. 2011 May; 49(5): 1997-9.

 

12.        Yeboah-Manu D, Peduzzi E, Mensah-Quainoo E, Asante-Poku A, Ofori-Adjei D, Pluschke G, Daubenberger CA. Systemic suppression of interferon-gamma responses in Buruli Ulcer patients resolves after surgical excision of the lesions caused by the extracellular pathogen mycobacterium ulcerans J Leukoc Biol. 2006 Jun; 79(6): 1150-6

Books & book chapters

University Reader series

 Yeboah-Manu D, Asante-Poku A, Otchere ID, Bonsu F, et al. (2013) Tuberculosis (TB): Local solution for a Global Public Health problem. IN Towards effective disease control in Ghana: Research and policy implications 5(2): Chp. 10, pg.111-158. Sub-Saharan publishers

Contact us

Noguchi

P.O. Box LG 581
Legon, Accra

+233 030 2501178/79

logo