Parasitology

Prof. Michael David Wilson

Prof. Michael David Wilson

Parasitology Department

Name (qualifications):

Michael David Wilson PhD (Salford), MSc (London) BSc (Ghana)

Research Area Strengths (List): e.g. Bioinformatics, Epidemiology, Insect Taxonomy

Evolutionary Biology, Computational Biology, Biology of Soil-transmitted Helminthiasis and Simulium damnosum s.l. morpho-taxonomy

Email(s): mwilson@noguchi.ug.edu.gh

Website/Twitter/Facebook: www.noguchimedres.org

Research Group(s):

Neglected Tropical Diseases (NTD), Vector Research.

 

Ongoing Research (please add value of funding and funding organization)

  1. Project title: Noguchi Institute for Neglected Tropical Diseases Elimination (NIINE) Funding Amount and Agency: $1,888,997, NIAID/NIH (2017-2022)
  2. Computer-aided Drug Discovery Programme for Buruli ulcer, Hookworm and Schistosomiasis. Funding Amount and Agency: None as it was recently initiated.

 

Affiliated Departments/Institutions:

  1. Professor of Parasitology, Department of Parasitology, NMIMR, Ghana
  2. Affiliate Professor, Stritch School of Medicine, Loyola University of Chicago, USA
  3. Director, NCDs Support Centre for Africa Centre NMIMR, Ghana
  4. Program Director, Noguchi Institute Initiative for NTDs Elimination NMIMR, Ghana
  5. Senior Scientific Advisor, NTDs Support Centre for Africa (formerly, LF support Centre for Africa)
  6. Member, Research Advisory Board, HopeXchange Medical Centre, Kumasi, Ghana
  7. Co-Director, Yale-Ghana Global Health Partnership NMIMR, Ghana

 

Professional Organizations:

Member, American Society of Tropical Medicine and Hygiene

Member, American Committee of Global Health

Member, American Committee on Medical Entomology

 

Research Interests (250 words maximum):

I have over 38 years of experience in diseases prevention and control; including 5 years as a biologist with the research arm of the WHO Onchocerciasis Control Programme in West Africa, and Project Leader of an international team of experts that established the feasibility and developed the operational strategy to eliminate onchocerciasis through the eradication of Simulium damnosum vectors, from the Island of Bioko, Equatorial Guinea (1999-2003). I was a Programme Manager of the West African Centre for International Parasite Control which provided training and technical advice to managers of national soil-transmitted helminthiasis (STH) control programmes in seven West African countries. I served on the Advisory Committee, Mebendazole Donation Initiative - a global initiative by Johnson and Johnson Inc. in its formative years, as a soil-transmitted helminthiasis control expert (2005-2009). From 2009-2011 I managed from Geneva, four disease-specific reference groups (DRGs) of world-renowned experts on; Malaria, Dengue and Viral Diseases of Public Health Importance, Chagas disease, Human African Trypanosomiasis and Leishmaniasis, and Helminthiasis (partial) established by WHO/TDR. The DRGs reviewed the evidence, identified gaps in knowledge and opportunities, and top-level research priorities that could significantly impact global health. I am currently the Program Director of an NIAID/NIH U19 grant award titled Noguchi Institute Initiative for NTDs Elimination (NIINE) having completed a research project (RO1) on the epidemiology of hookworm infections in Ghana (2012-2017) and another on Climate Change and Onchocerciasis in the Black Volta River Basin of Ghana funded by DfID/IDRC, Canada (2009-2011). My research interest focuses on local and global issues regarding sustainable control/elimination of neglected tropical diseases. My passion is training and mentoring young researchers and students from diseases-endemic countries.

Current Research Supervision:

Visiting Fellows

Dr. Adel Driss (Morehouse School of Medicine, Atlanta)

Postdocs:

Dr. Jewelna AB Akorli (WACCBIP)

PhD

Richard Akuffo, School of Public Health, University of Ghana

MPhil

Joshua Labadah, WACCBIP

 

Keywords

Key/Notable Publications (max 10)

  1. SAMUEL K. KWOFIE, BISMARK DANKWA, KWEKU S. ENNINFUL ET AL. (2019). Molecular docking and dynamics simulation studies predict Munc18b as a target of mycolactone: a plausible mechanism for granule exocytosis impairment in Buruli ulcer pathogenesis. Toxins, 11, 181
  2. SAMUEL K. KWOFIE, BISMARK DANKWA, EMMANUEL A. ODAME, FRANCIS E. AGAMAH, LADY P. A. DOE, JOSHUA TEYE, ODAME AGYAPONG, WHELTON A. MILLER III, LYDIA MOSI AND MICHAEL D. WILSON (2018). In Silico Screening of Isocitrate Lyase for Novel Anti-Buruli Ulcer Natural Products Originating from Africa. Molecules, 23, 1550; doi:10.3390/molecules23071550.
  3. BRIGHT KOJO AZUMAH, PHYLLIS ADDO, ALFRED DODOO, LYDIA MOSI, GORDON AWANDARE, MICHAEL WILSON (2017). Experimental demonstration of the possible role of Acanthamoeba polyphaga in the infection and disease progression in Buruli ulcer (BU) using ICR mice. PLoS ONE 12(3): e0172843.
  4. MICHAEL D WILSON, DANIEL A. BOAKYE, LYDIA MOSI, KINGSLEY ASIEDU (2011). In the case of transmission of Mycobacterium ulcerans in Buruli ulcer disease Acanthamoeba species stand accused. Ghana Medical Journal. 45(1): 31-34
  5. LAUVE RACHEL TCHOKOUAHA YAMTHE et al. (2017). Marine algae as source of novel antileishmanial drugs: a review. Marine Drugs; 15: 323; doi:10.3390/md15110323
  6. PRECIOUS A. DZORGBE MATTAH, GODFRED FUTAGBI, LEONARD K. AMEKUDZI, MEMUNA M. MATTAH, DZIEDZORM K. DE SOUZA, WORLASI D. KARTEY-ATTIPOE, LANGBONG BIMI AND MICHAEL D. WILSON. (2017). Diversity in breeding sites and distribution of Anopheles mosquitoes in selected urban areas of southern Ghana. Parasites and Vectors, 10: DOI 10.1186/s13071-016-1941-3
  7. GEOFFREY R. ATELU, NANCY O DUAH, MICHAEL WILSON (2017). Carriage of sub-microscopic sexual and asexual Plasmodium falciparum stages in the dry season at Navrongo, Ghana. Ghana Medical Journal; 50(4): 220-227
  8. JAMES LEE CRAINEY, JACOB HURST, POPPY H.L. LAMBERTON, ROBERT A. CHEKE, CLAIRE E. GRIFFIN, MICHAEL D. WILSON, CLÁUDIA PATRICIA MENDES DE ARAÚJO, MARIA-GLORIA BASÁÑEZ, RORY J. POST. (2017). A Simulium damnosuml. Wolbachia prophage relic, sr1WOdamA1, contains an SpvB gene and occurs adjacent to the wDam FtsZ cell division gene. Frontiers in Microbiology, section Evolutionary and Genomic Microbiology 8: 852.
  9. DEBBIE HUMPHRIES, SARA NGUYEN, SUNNY KUMAR, JOSEPHINE E QUAGRAINE, JOSEPH OTCHERE, LISA M HARRISON, MICHAEL D WILSON, MICHAEL CAPPELLO (2016). Effectiveness of albendazole for hookworm varies by community and correlates with nutritional factors: A cross-sectional study of school-age children in Ghana. American Journal of Tropical Medicine and Hygiene: 347–354
  10. MICHAEL D. WILSON, DZIEDZOM K. DE SOUZA AND IRENE AYI (2016). Soil-transmitted Helminthiasis. In, Neglected Tropical Diseases. John Gyapong and Boakye Boatin (editors) Springer Heidelberg, pp 289-317.

The Noguchi Memorial Institute for Medical Research (NMIMR), set up in 1979 as a semi autonomous institute of the University, is the leading biomedical research facility in Ghana.

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