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Title:

Professor

Name:

Professor Kennedy Kwasi Addo

Academic Qualification

DVM, PhD

Professional Qualification

 

Email address:

kaddo@noguchi.ug.edu.gh

Cell phone

 

Telephone:

+233-302-501178/9; +233-243334869

Schools attended

 

Department:

Bacteriology

Short Bios

Professor Kennedy Kwasi Addo is an Associate Professor with NMIMR. He holds a DVM General Vet. MedicinefromUniversity of Veterinary Medicine, Kosice,Czechoslovakia,a PhD Vet. Public Health from University of VeterinaryMedicine, Kosice,Slovakia and a Post-Doctoral Diploma, TB Control & Epidemiology from Research Institute of Tuberculosis, Tokyo,Japan.

 

Reaearch/ Administrative Role

 

Research Interests:

1.Mycobacterial infections

2. Bacterial sexually transmitted infections.

3. TB/HIV co-infection

4. Microbiological quality of food and water

5.Bacterial zoonoses

Research Projects Completed (Within Past 5 Years)

1.University of Ghana research fund 5th call for proposals

Project title: Prevalence of TB infection among cattle and animal handlers: an insight into abattoir practices in Accra 2012-2014 GHS 30,000

Role:Principal Investigator

 

2. Evaluation of the BACTECTM Myco-F/Lytic medium for the detection of TB in blood from HIV positive patients funded by Becton Dickinson Diagnostic Systems, 2012-2013 USD 134,000

Role: Co-investigator

 

3. Sexually Transmitted Diseases (STD) Surveillance Characterizing Gonorrhoea and Chlamydia Prevalence and Gonorrhoea Resistance Profiles in Ghana funded by the Global Emerging Infectious Disease Surveillance (GEIS), Armed Forces Health Surveillance Center, Silver Spring, Maryland, 2011-2013 USD 100,000

Role: Co-investigator

 

4. Investigating the prevalence of Shigella and/or Enterotoxigenic Escherichia coli infections in Ghana and to measure the natural immune responses to these infections funded by European Union STOPENTERICS Consortium, 2011-2015 USD 200,000.

Role: Co-investigator

 

5.Assessing TB Disease Prevalence in Ghana Through a Population Based Survey funded by the Global Fund, Dutch Government and WHO, 2011-2013. USD 3.0 million.

Role: Co-Principal Investigator

 

6. One Health Initiative. African Research Consortium for Ecosystem and Population Health: Expanding Frontiers in Health funded by the Wellcome Trust, 2009-2014 GBP 362,000.

Role: Co-Principal Investigator

 

7.Genotypic and phenotypic characterization of Mycobacterium africanum, funded by the Leverhulme – Royal Society (UK) Award, 2009-2012 GBP 150,000.

Role: Co-investigator

 

8.Second HIV and Sexually Transmitted Infections study among Female Sex Workers in Accra and Kumasi funded by United States Agency for International Development (USAID) through the SHARP Project (Strengthening HIV/AIDS Response Partnerships), 2009-2010 USD 100,000.

Role: Co-investigator

 

9.Drug Resistant Tuberculosis in Ghana: Molecular Epidemiology and Relations with Species in Mycobacterium tuberculosisComplex, funded by the Ministry of Education, Culture, Sports, Science and Technology of Japan, 2008 – 2011 USD 66,000.

Role: Co-Principal Investigator

 

10.Molecular Epidemiology of Tuberculosis in Ghana: Genotyping of M. tuberculosis Strains in Refugee and Non-refugee Populations, funded by the World Health Organization and Ghana Health Service, 2008-2010 USD 80,000.

Role: Co-investigator

 

11.Nationwide Survey to Determine the Prevalence of TB/HIV Co-infection in Ghana funded by the Global Fund to Fight Tuberculosis, HIV/AIDS and Malaria, 2007-2009 USD 96,000.

Role: Principal Investigator

 

12.Study entitledEliminating milk-borne public health risks in Ghana: assessing tuberculosis, brucellosis and enteropathogenic Escherichia coli hazards and the occurrence of antimicrobial agents in milkfunded by Ghanaian-Dutch collaboration for health research and development, 2006-2008 USD 50,000.

Role: Principal Investigator

 

13.Survey to Determine the Prevalence of Tuberculin Skin Sensitivity in Ghanaian School Children, funded by the Global Fund to Fight Tuberculosis, HIV/AIDS and Malaria, 2003-2006 USD 180,000.

Role: Principal Investigator

 

14.Training of Private Health Sector Laboratory Personnel in TB Microscopy and Quality Assurance as part of Private Health Sector Involvement in TB Control Management in Accra, Kumasi and Tema Metropolitan Areas, funded by the Global Fund to Fight Tuberculosis, HIV/AIDS, and Malaria, 2003-2008 USD 50,000.

Role: Principal Investigator

 

15. Nationwide survey on resistance to first line anti-tuberculosis drugs in Ghana funded by West African TB Research Initiative and Global Fundto Fight Tuberculosis, HIV/AIDS, and Malaria, 2006-2008 USD 120,000.

Role: Principal Investigator

 

16.Control and management of drug resistant tuberculosis in selected Ghanaian Prisons, funded by Ghanaian-Dutch collaboration for health research and development, 2006-2007 USD 50,000.

Role: Co-Investigator

 

17.Nationwide assessment of private laboratory capacity to support TB care and control in Ghana, funded by Ghanaian-Dutch collaboration for health research and development, 2006-2007 USD 50,000.

Role: Co-Investigator

18.HIV and Sexually Transmitted Infections study among Female Sex Workers in Accra and Kumasi funded by United States Agency for International Development (USAID) through The Futures Group under the SHARP Project (Strengthening HIV/AIDS Response Partnerships) 2006-2007 USD 100,000

Role: Co-investigator

 

19.(TB) Infectious Diseases Project funded by Japan International Co-operation Agency (JICA)/NMIMR in Improving TB Diagnosis in Ghana, Middle-Level Manpower Training, TB Quality Assurance, Culture and Characterization of aetiological agents of TB and Anti-TB Drug Susceptibility Assay, 1999-2003 USD 100,000.

Role: Principal Investigator

 

20.Project entitled “Developing Safety Strategies and Procedures through Reduction of Food Hazards in Street-Vended to Improve Food Security for Consumers, Street Food Vendors and Input Suppliers” funded by The Department for International Development (DFID), UK, 2002-2004 GBP 195,000.

Role: Co-Investigator

 

On-Going Research Projects

1. “African Science Partnership for Intervention Research Excellence (Afrique One – ASPIRE)” funded by the Wellcome Trust under “Developing Excellence in Leadership, Training and Science (DELTAS) Africa Award 2016-2021 EURO 7,046,548

Role: Co-Principal Investigator

 

2. “Understanding the host response to tuberculosis for biomarker discovery: peripheral blood transcriptional signatures of Ghanaians TB patients and close household contacts 2016-2018

Role: Co-Principal Investigator

 

3. “Molecular epidemiology of Methicillin Resistant Staphylococcus aureus (MRSA) among livestock and farm attendants funded by the University of Ghana research fund 9th call for proposals 2016-2017 at the cost of USD10,000

Role: Co-Principal Investigator

 

 

4. Co-Principal Investigator “Relevance of macrophage Migratory Inhibitory Factor (MIF) low and high -producer phenotypes to outcome of tuberculosis infection in a Ghanaian cohort” funded by TWAS and University of Ghana research fund 9th call for proposals 2016-2017 at the cost of USD50,000

Role: Co-Principal Investigator

 

5.“Prevalence of Methicillin resistant Staphylococcus aureus (MRSA) and Extended spectrum beta-Lactamase (ESBL) producing bacteria associated with Surgical Site Infections in a Military and Civilian Hospital in Ghana” funded by Global Emerging Infectious Disease Surveillance (GEIS), Armed Forces Health Surveillance Center, Silver Spring, Maryland, USA 2016-2017 USD 133,000

Role: Co- Investigator

 

Publications:

1.      Bjerrum, S., Oliver-Commey, J., Kenu E., Lartey, M., Newman,M. J., Addo, K. K., Hilleman, D., Andersen, A. B., Johansen, I. S. (2016): Tuberculosis and non-tuberculous mycobacteria among HIV infected individuals in Ghana. Tropical Medicine & International Health 07/2016; Volume 21 No 9 pp 1181-1190 DOI: 10. 1111/TMI.12749

 

2.      Egyir, B.,Oteng, A. A., Owusu, E., Newman, M. J., Addo, K. K., Larsen, A.R. (2016): Characterization of Staphylococcus aureus from Human ImmunodeficiencyVirus (HIV) patients in Accra, Ghana. Journal of Infection in Developing Countries 10(5):453-456. doi:10.3855/jidc.7428

 

3.      Bjerrum, S., Kenu E., Lartey, M., Newman,M. J., Addo, K. K., Andersen, A. B., Johansen, I. S. (2015): Diagnostic accuracy of the rapid urine lipoarabinomannan test for pulmonary tuberculosis among HIV-infected adults in Ghana-findings from the DETECT HIV-TB study. BMC Infect Dis 15(1): 407 DOI 10.1186/s12879-015-1151-1

 

4.      Egyir, B., Guardabassi, L., Moneck, S., Addo, K. K.,Newmann, M. J., Larsen, A. R. (2015) Methicillin-resistant Staphylococcus aureus strains from Ghana include USA300. Journal of Global Antimicrobial ResistanceDOI: http://dx.doi.org/10.1016/j.jgar.2014.11.0063: 26–30

5.      Addo, K. K., Adjei, V. Y., Mensah, G. I., Jackson-Sillah, D. (2014): Microbial quality and antibiotic residues in raw beef from selected abattoirs in Accra, Ghana. International Journal of Tropical Disease and Health in press

 

6.      Egyir, B., Guardabassi, L., Moneck, S., Addo, K. K., Newmann, M. J., Larsen, A. R. (2014): DNA based Micro Array Profiling of Virulence Determinants and Antimicrobial Resistance of Methicillin Resistant Staphylococcus aureus from Ghana. Journal of Global Antimicrobial Resistance in press

 

7.      Mensah G. I., Addo, K. K.,  Tetteh, J. A. K., Sowah, S. A., Loescher, T., Geldmacher, C., Jackson-Sillah, D. (2014): Cytokine response  to   selected  MTB  antigens in Ghanaian TB patients, before and at 2 weeks of anti-TB therapy is characterized by high expression of IFN-gamma and Granzyme B  and inter- individual variation. BMC Infectious Diseases 14:495

 

8.      Kato, T., Addo, K. K., Nartey, N., Nyarko, A. K., Bonsu, F. A., Mitari, S. (2014): First susceptibility testing of Mycobacterium tuberculosis for second-line anti-tuberculosis drugs in Ghana. Tropical Medicine and Health doi:10.2149/tmh.2013-16

 

9.      Addo O.H., Addo, K. K.,Bimi, L. (2014): Water Handling And Hygiene Practices On The Transmission Of Diarrhoeal Diseases And Soil Transmitted Helminthic Infections In Communities In Rural Ghana. Civil and Environmental Research 6 (1): 68-79.

 

10.  Egyir, B., Guardabassi, L., Esson, J., Nielsen, S. S., Newman, M. J., Addo, K. K., Larsen, A. R. (2014): Insights into nasal carriage of Staphylococcus aureus in an urban and a rural community in Ghana. PLoS ONE 9(4): e96119. doi:10.1371/journal.pone.0096119

 

11.  Egyir, B., Guardabassi, L.,Sørum, M., Nielsen, S. S., Kolekang, A., Frimpong, E., Addo, K. K. Newman, M. J., Larsen, A. R. (2014): Molecular Epidemiology and Antimicrobial Susceptibility of Clinical Staphylococcus aureus from Healthcare Institutions in Ghana. PLoS ONE 9(2): e89716. doi:10.1371/journal.pone.0089716

 

12.  Jackson-Sillah, D., Cliff, J. M., Mensah, G. I., Dickson, E., Sowah, S., Tetteh, J. K. A., Addo, K. K., Ottenhoff, T. H. M., Bothamley, G., Dockrell, H. M., (2013). Recombinant ESAT-6-CFP10 Fusion Protein Induction of Th1/Th2 Cytokines andFoxP3 Expressing Treg Cells in Pulmonary TB. PLoS ONE 8(6): e68121. doi:10.1371/journal.pone.0068121

 

13.  9. Egyir B.,Guardabassi, L., Nielsen, S. S., Larsen, J., Addo, K. K., Newman, M. J., Larsen, A. R.(2013): Prevalence of Nasal Carriage and Diversity of Staphylococcus aureus Among Inpatients and Hospital staff at Korle Bu Teaching Hospital, Ghana. Journal of Global Antimicrobial Resistance 1: 189 –193

 

14.  Odonkor, S. T., Addo, K. K. (2013): Microbiologicalquality of water sources from the largest district in Greater-Accraregion, Ghana: a call for innovational schemes towardsrural water resources management. International Journal of Science, Environment and Technology 2 (4): 536 – 555.

 

15.  Odonkor, S. T., Addo, K. K. (2013): Bacteriological profile and physico-chemical quality of ground water: a case study of bore hole water sources in a rural Ghanaian community. International Journal of Current Microbiology and Applied Science 2(8): 21-40.

 

16.  Addo O. H., Addo K. K.,Bimi, L. (2013): Sanitation and its impact on the bacteriological quality of water: A study in three communities in Ghana. African Journal of Food, Agriculture, Nutrition and Development 13(5):8258-8272.

17.  Odonkor, S. T., Newman, M. J., Addo, K. K. (2012): Prevalence and antibiotic susceptibility profile of methicillin resistant Staphylococcus aureus in Accra, Ghana. Microbiology Research 3:e20.

 

18.  Addo,K. K., Mensah,G. I., Aning,K. G, Nartey,N., Nipah,G.K., Bonsu, C., Akyeh, M. L., Smits,H.L. (2011): Microbiological quality and antibiotic residues in informally marketed raw cow milk within the coastal savannah zone of Ghana. Tropical Medicine & International Health 16 (2): 227-232.

 

19.  Addo,K. K., Mensah,G. I., Nartey,N., Nipah,G.K., Mensah, D., Aning,K. G, Smits,H.L. (2011): Knowledge, attitudes and practices (KAP) of herdsmen in Ghana with respect to milk-borne zoonotic diseases and the safe handling of milk. Journal of Basic and Applied Scientific Research 1 (10):1556-1562.

 

20.  Mensah,G. I., Addo,K. K., Aning,K. G, Nartey,N., Nipah,G.K., Smits,H.L. (2011): Brucella abortus antibodies in raw cow milk collected from kraals within the coastal savannah zone of Ghana. Journal of Basic and Applied Scientific Research 1(8): 942-947.

 

21. Odonkor, S. T., Addo, K. K. (2011): Evaluation of three methods for detection of Methicillin Resistant Staphylococcus aureus (MRSA). International Journal of Biological & Medical Research 2 (4):1031 – 1034.

 

22. Odonkor, S. T., Addo, K. K. (2011): Bacteria resistance to antibiotics: Recent trends and challenges. International Journal of Biological & Medical Research 2 (4):1204 – 1210.

 

23.  Odonkor, S. T., Mahami, T., Addo, K. K. (2011): Antimicrobial sensitivity patterns of urine isolates from a large Ghanaian hospital. International Research Journal of Microbiology2 (7):237-241.

 

24. Addo,K. K., van den Hof, S., Mensah,G. I., Hesse,A., Bonsu,C., Koram,K.A., Afutu,F.K., Bonsu,F. A. (2010): A tuberculin skin test survey among Ghanaian school children. BMC Public Health 10:35

 

25. Addo, K. K., Yeboah-Manu, D., Dan-Dzide, M., Owusu-Darko, K., Caulley, P., Mensah, G. I., Minamikawa, M., Leinhardt, C., Bonsu, F.A., Ofori-Adjei, D. (2010):Diagnosis of tuberculosis in Ghana: the role of laboratory training.Ghana Medical Journal 44 (1): 31-36.

 

26.  Addo, K. K., Mensah, G. I., Donkor B., Bonsu, C., Akyeh, M. L. (2009): Bacteriological quality of bottled water sold on the Ghanaian market. African Journal of Food, Agriculture, Nutrition and Development 9 (6): 1378-1387.

 

27.  Addo, K. K., Mensah, G. I., Bekoe, M., Bonsu, C., Akyeh, M. L. (2009): Bacteriological quality of sachet water produced and sold in Teshie-Nungua suburbs of Accra, Ghana. African Journal of Food, Agriculture, Nutrition and Development 9 (4): 1019-1030.

28.  24.Addo O. H., Addo K. K., Bimi, L. (2009): Soil Transmitted Helminth Infections among school-aged children in three communities in Ghana. Applied Science and Technology (Fifth Lecture Series) 1: 94 – 101.

 

29. Bimi L., Amoah, D. K., Hotor, V. E., Addo, K. K. (2008): Important bacterial contaminants of public payphones on the campus of the University of Ghana. Ghana Journal of Allied Health Sciences 2 (1): 10-14.

 

30.  Addo, K. K., Mensah, G. I., Bonsu, C., Akyeh, M. L. (2007): Food and its preparation conditions in hotels in Accra, Ghana: a concern for food safety? African Journal of Food, Agriculture, Nutrition and Development 7 (5): 1-12.

 

31. Addo, K. K., Owusu-Darko, K., Yeboah-Manu, D., Dan-Dzide, M., Caulley, P., Minamikawa, M., Bonsu, F., Leinhardt, C., Akpedonu, P., Ofori-Adjei, D. (2007):Mycobacterial species causing pulmonary tuberculosis at the Korle-Bu teaching hospital, Accra, Ghana. Ghana Medical Journal 41 (2): 52-57.

 

32.  Newman M. J., Addo, K. K., Aboagye, S., Bonsu F. A., Caulley, P., Hesse, I. F. A., Neequaye, A. R., Kudzawu, S. (2007): Culture and sensitivity of mycobacterial isolates from pulmonary tuberculosis cases classified as treatment failures in a teaching hospital. West African Journal of Medicine 26 (2): 131-133.

 

33. Addo, K. K., Owusu-Darko, K., Dan-Dzide, M., Yeboah-Manu, D., Caulley, P., Minamikawa, M., Bonsu, F., Leinhardt, C., Akpedonu, P., Ofori-Adjei, D. (2006): Situation analysis of TB microscopy centres in Ghana. International Journal of Tuberculosis and Lung Disease 10 (8): 870-875.

 

34. Addo, K. K., Dan-Dzide, M., Yeboah-Manu, D., Owusu-Darko, K., Caulley, P., Minamikawa, M., Bonsu, F., Leinhardt, C., Akpedonu, P., Ofori-Adjei, D. (2006): Improving laboratory diagnosis of TB in Ghana: the impact of a quality assurance system. International Journal of Tuberculosis and Lung Disease 10(7): 812-817.

 

35.  Rodrigues, F. K., Armah, G., Virrankoski, V., Addo, K. K., Osae-Addae, A. (2006): Isolation, Purification and Partial Characterization of new Bacteriophages for Shigella dysenteriae. Journal of Ghana Science Association 8 (2): 38-45.

 

36.  Agbodaze, D., Nmai, P. N. A., Mills-Robertson, F. C., Yeboah-Manu, D., Owusu-Darko, K., Addo, K. K. (2005): Microbiological quality of “Khebab” consumed in Accra Metropolis. Ghana Medical Journal 2: 46-49.

 

37. Addo, K. K. (2000): The upsurge of tuberculosis in Ghana. Bi-Annual Journal of the Ghana Veterinary Medical Association, 1: 9-11.

 

38.  Addo, K. K., Kapitancik, B., Dubinsky, P. (1998): Economic losses due to outbreak of mycobacterioses in pigs in Eastern Slovakia. Folia Veterinaria, 4:13 – 15.

 

39. Addo, K. K., Kapitancik, B., Velebny, S., Hrckova, G., Mattova, J., Dubinsky, P. (1998): The experimental immunization of cattle against tuberculosis by liposomized BCG vaccine. Folia Veterinaria, 3:153 – 157.

 

40. Addo, K. K., Kapitancik, B. (1998): Control of tuberculosis in Ghana. Folia Veterinaria, 2:115 – 118.

 

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