Prof Regina Appiah-Opong inducted as Fellow of the Ghana Academy of Arts and Sciences

 Professor Regina Appiah-Opong, Professor of Toxicology/Pharmacology and Head of the Department of Clinical Pathology, on Tuesday, 23rd November, 2021, was inducted as a fellow of the Ghana Academy of Arts and Sciences.

 The Institute wishes to congratulate her on her induction. The ceremony also witnessed the induction of the Council Chair of the University of Ghana, Justice Sophia Akuffo, the Vice Chancellor, Prof. Nana Aba Amfo, as well as 5 other faculty members of the University.

 

Profile – Regina Appiah-Opong, PhD

 Professor Regina Appiah-Opong is an Associate Professor of Toxicology and Head of the Department of Clinical Pathology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana. She is also a Part-time Lecturer at the Department of Biochemistry, Cell and Molecular Biology, College of Basic and Applied Sciences, University of Ghana. She is a leading Toxicologist in Ghana, working to develop drugs mainly from natural sources as anticancer, antimalarial, antioxidant, anti-HIV, anti-trypanosomal, anti-Buruli ulcer, anti-tuberculosis, anti-leishmanial and anti-COVID-19 agents. Her current focus is on anticancer, antimalarial and anti-COVID-19 agents. Professor Appiah-Opong has a keen interest in cytochrome P-450-mediated drug-drug, herb-drug and food-drug interactions well as pharmacokinetics. Her research has resulted in a patent that was filed on anti-trypanosomal compounds derived from the plant Morinda lucida.

 Professor Appiah-Opong was among the research group that adapted the 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT)-based colorimetric assay for high-throughput screening for antimalarial agents. She also significantly contributed to the drug efficacy studies on a class of anti-HIV drugs known as protease inhibitors, effective against HIV-1 subtype B found which originates from some western countries. This study revealed that most of the Ghanaian HIV-1 were of subtype AG which was less susceptible to the protease inhibitors. In vitro drug interactions studies performed on selected Ghanaian medicinal plants have also indicated the herb-drug interaction potentials of these medicines if co-administered with conventional medicines. She has over 80 publications in peer-reviewed journals and 3 book chapters.

 Professor Appiah-Opong is a mentor for several young scientists including postdoctoral fellows, Ph.D, MPhil and BSc students from tertiary institutions in Ghana and other countries.

 

 

Prof. Appiah-Opong and Professor Alexander Nyarkoh, former Director, NMIMR

Prof. Appiah-Opong and other inductees

Prof. Appiah Opong and Dr. Daniel Arhinful, Epidemiologist, MMIMR

 

The Noguchi Memorial Institute for Medical Research (NMIMR), set up in 1979 as a semi autonomous institute of the University, is the leading biomedical research facility in Ghana.

© 2021 NMIMR

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